Restylane and Perlane

Are you concerned about skin aging, fine lines, facial wrinkles, creases and furrows, sunken cheeks, skin depressions, and/or acne scars? If so, you could be a candidate for Restylane or Perlane!

Restylane and Perlane are FDA-approved gel dermal fillers made of a biodegradable, non-animal stabilized hyaluronic acid (NASHA). Hyaluronic acid is a natural substance found in all living organisms and provides volume and fullness to the skin. Unlike other hyaluronic acid products, Restylane and Perlane are produced biotechnologically by natural fermentation in a sterile laboratory environment. Since they are not derived from animal sources, the risk of transmitting diseases between species or of eliciting allergic reactions in patients who are sensitive to common foods, such as beef, chicken, and eggs are significantly diminished. Restylane and Perlane are available only through a licensed practitioner and does not require any allergy or skin testing prior to injection.

Restylane can be used to add volume and fullness to the skin in order to correct moderate facial wrinkles and folds, such as:

  • The lines from your nose to the corners of your mouth (also known as the nasolabial folds) as well as lip enhancement
  • Sunken cheeks
  • Acne scars
  • Laugh line
  • Marionette lines
  • Lipstick lines


Perlane is made of larger gel particles than Restylane and is injected deeper within the skin to treat more severe cases of facial wrinkles and folds.

Upon injection, the gel integrates into dermal tissue then attracts and binds to water molecules to help maintain volume. It is gradually degraded by the body’s own mechanism and disappears without any residue. Results can be seen immediately following treatment and lasts for up to 6 months. Some patients may achieve results lasting longer than 6 months, depending upon the injection site.

Both Restylane and Perlane contain Lidocaine, which helps to minimize discomfort during treatments. Side effects are typically mild in severity and normally last less than 7 days in nasolabial folds and less than 14 days in lips. Swelling may be more likely in patients under 36 years, while bruising may be more likely in patients over 35 years.

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